Search on: SINGLE-STRAND SPECIFIC DNA AND RNA ENDONUCLEASES 
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Descriptor English:   Single-Strand Specific DNA and RNA Endonucleases 
Descriptor Spanish:   Endonucleasas Específicas del ADN y ARN con un Solo Filamento 
Descriptor Portuguese:   Endonucleases Específicas para DNA e RNA de Cadeia Simples 
Tree Number:   D08.811.277.352.335.350.700
D08.811.277.352.355.325.700
D08.811.277.352.355.350.820
D08.811.277.352.700.350.850
Definition English:   Enzymes that catalyze the endonucleolytic cleavage of single-stranded regions of DNA or RNA molecules while leaving the double-stranded regions intact. They are particularly useful in the laboratory for producing "blunt-ended" DNA molecules from DNA with single-stranded ends and for sensitive GENETIC TECHNIQUES such as NUCLEASE PROTECTION ASSAYS that involve the detection of single-stranded DNA and RNA. 
History Note English:   2009(1990) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   24528 
Unique Identifier:   D015719 

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